The Apothecary Diaries Season 2 Opening Theme 'Hyakkaryōran' Unveils Captivating English Version for Global Fans

The excitement for The Apothecary Diaries Season 2 has reached new heights with the highly anticipated release of an all-new English rendition of its vibrant opening theme, “Hyakkaryōran.” This captivating track, originally performed by the acclaimed Lilas Ikuta, known for her dynamic solo career and powerful vocals with YOASOBI, has been a cornerstone of the series' appeal. It perfectly encapsulates the intricate blend of historical mystery and compelling drama that fans adore.

Now, international audiences can immerse themselves even deeper, thanks to a masterfully recorded and performed English cover by Dima Lancaster. Lancaster's thoughtful adaptation of the lyrics ensures that the thematic richness and emotional resonance of the original composition are beautifully preserved. This offers a fresh, accessible perspective to this beloved anime's musical introduction. The English version is readily available on platforms like YouTube, inviting a broader global community to experience the magic of “Hyakkaryōran” anew.

The Apothecary Diaries Season 2 made its grand premiere on Nippon TV’s FRIDAY ANIME NIGHT in early 2025, embarking on a continuous two-cour run that has since captivated viewers. The series draws its narrative brilliance from the acclaimed light novel series penned by Natsu Hyūga and exquisitely illustrated by Touko Shino, with digital publication handled by J-Novel Club. Under the expert production of TOHO animation, the anime continues to unravel the complex web of palace intrigues and fascinating medicinal enigmas surrounding its brilliant protagonist, Maomao. She is a sharp-witted apothecary navigating the treacherous world of imperial China.

This season also introduces exciting new talent, including Asami Seto in the role of the maid Shisui, and features a fresh ending theme, “Shiawase no Recipe,” performed by Dai Hirai, further enriching the auditory landscape of the series.

The original Japanese “Hyakkaryōran” already stands as a testament to the anime’s immense popularity, having soared to number one on the weekly digital singles charts upon its release. Complementing this widespread appeal, a special exhibition celebrating the series' cultural impact and stunning visual artistry was successfully held at MATSUYA GINZA in early 2025, drawing legions of fans. With the advent of the English version, The Apothecary Diaries Season 2 is poised to forge even deeper connections with its worldwide fanbase, amplifying the global reach and appreciation for this meticulously crafted anime adaptation. The seamless integration of breathtaking visuals, a gripping storyline, and profoundly evocative music firmly establishes The Apothecary Diaries as a preeminent title in the contemporary anime landscape.