Fantasy Isekai 'Potion, Waga Mi o Tasukeru' Bolsters Cast with Three New Stars for Autumn 2025 Debut!

The highly anticipated anime adaptation of the beloved light novel series, Potion, Waga Mi o Tasukeru, has ignited fan excitement with the announcement of three dynamic new cast members, setting the stage for its grand premiere on October 2, 2025, across Japan. This latest revelation builds on the previously unveiled lead cast, featuring the talented Kaede Hondo as the resourceful protagonist Kaede and Takeo Otsuka lending his voice to the enigmatic Asuru.

The newly introduced vocal talents promise to enrich the fantastical narrative: Yū Kobayashi steps into the shoes of Caldeno, a captivating female wolf character; Miharu Hanai embodies the whimsical fairy Nina; and Yurika Moriyama takes on the formidable role of Rei, the intrepid leader of the dragon hunters. This strategic expansion of the ensemble cast offers an enticing glimpse into the vibrant and multifaceted world that the anime is poised to explore, promising a tapestry of diverse characters and enthralling interactions.

Guiding this ambitious project is director Mikiko Furukawa, celebrated for her work on Moriarty’s Perfect Crime, while bermei.inazawa crafts an immersive musical score. Yuichi Imaizumi, known for his contributions to Medalist, oversees the intricate sound direction. Animation support is provided by Studio KAIBA, with the primary animation production spearheaded by the skilled teams at IMAGICA Infos and Imageworks Studio, all under the discerning eye of production supervisor Kazuya Takahashi.

At its heart, Potion, Waga Mi o Tasukeru draws from Akira Iwafune’s original isekai fantasy light novel, brought to life by the illustrations of Sunaho Tobe. The story chronicles the extraordinary journey of an ordinary high school girl named Kaede, who finds herself transported to a fantastical realm, suddenly possessing a mystical tome that grants her the power to conjure potent potions. The series is poised to deliver an exhilarating blend of fantasy adventure intertwined with a deeply character-driven storyline.

Originating as a captivating web novel, the series found its official publishing home under Shufunotomo’s Hero Bunko imprint in April 2015, subsequently expanding into 10 volumes and inspiring a manga adaptation that launched in September 2023. Devotees of the isekai and fantasy genres are eagerly counting down to the anime’s debut, which promises a refreshing and imaginative take on survival and the art of potion-making in an unfamiliar world. This recent cast announcement, coupled with ongoing promotional efforts, paints a vivid picture of a richly developed universe and compelling character dynamics, further escalating the fervent anticipation for Potion, Waga Mi o Tasukeru among anime enthusiasts, both domestically and internationally.